Southern California Clinical and Translational Science Institute
Translating Science into Solutions for Better Health


The Southern California Clinical and Translational Science Institute (SC CTSI) is a multi-faceted research institute created by the University of Southern California (USC) and Children’s Hospital Los Angeles (CHLA) to translate scientific discoveries into solutions for better health.

Through the SC CTSI, researchers at USC and CHLA partner with other leading academic, clinical and community organizations to conduct clinical and translational research that will improve health in the diverse communities of Southern California. The SC CTSI seeks to achieve this goal by:

  • Engaging our diverse communities, their care providers and our researchers to establish clinical research priorities; identify barriers to research; and develop, demonstrate and disseminate innovative approaches to assure fully partnered clinical research across communities and the lifespan.
  • Promoting team science in clinical research by assembling interdisciplinary teams to design and conduct clinical studies and developing innovative approaches to address challenges in clinical research.
  • Expanding workforce capacity and capabilities by training researchers, staff, and clinical and community partners in team-based research in diverse populations.
  • Streamlining processes and creating efficient systems to support effective conduct of local and multi-center clinical research, in particular in diverse clinical and community settings.
  • Supporting and facilitating the conduct of multi-site network studies, adopting successful models, and developing and disseminating innovative strategies.

The SC CTSI was established in 2008. It has been supported since 2010 by a prestigious Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Science (NCATS) of the National Institutes of Health (NIH). The CTSA joins the SC CTSI to a national network of more than 60 medical research institutions that have a collective mandate to improve health through clinical and translational research and to improve clinical and translational research through development and implementation of national standards and best practices.

SC CTSI Core GroupsRead More

  • Administration
  • Clinical Research Support (CRS) at USC
  • Clinical Research Support  at CHLA
  • Clinical Research Informatics (CRI)
  • Community Engagement (CE)
  • Digital Innovation and Communication (DIC)
  • Evaluation and Improvement (EI)
  • Research Development (RD)
  • Workforce Development (WD)

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Supporting Researchers

SC CTSI provides services and resources to help researchers in various fields address critical health needs in L.A.