This study aims to determine if antibiotic exposure at sub-inhibitory concentrations induces toxin production by methicillin-resistant Staph aureus, causing more severe infection as evident by extent of skin necrosis in a murine skin abscess model.
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Research Pilot
Antibiotic Modulation of Staphylococcal Virulence Expression and Its Impact on Disease Severity in Murine Model of Infection
This study aims to determine if antibiotic exposure at sub-inhibitory concentrations induces toxin production by methicillin-resistant Staph aureus, causing more severe infection as evident by extent of skin necrosis in a murine skin abscess model.
NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.