Research paper on SC CTSI’s Community Health Worker training published in "Frontiers in Public Health"

A new paper published in "Frontiers in Public Health" highlights SC CTSI’s Fundamentals of Health Research training, a model designed to strengthen research understanding and engagement among community health workers.

By Andrea Diaz — July 02, 2025

SC CTSI’s Community Engagement Core recently published a research paper in Frontiers in Public Health titled “The Fundamentals of Health Research Training for Community Health Workers: A Mixed-Methods Study.” The paper was authored by Nicole Wolfe, PhD; Andrea Diaz; Brian Do-Golden, MPH, CHES; Esther Karpilow; Mayra Rubio-Diaz; and Michele D. Kipke, PhD. This paper presents The Fundamentals of Health Research, a training developed to build the capacity of community health workers/promotores de salud (CHW/Ps) to engage the public in clinical research. The training equips them with the knowledge and skills needed to serve as trusted research educators, advocates, and members of research teams.

Research paper on SC CTSI’s Community Health Worker training published in Frontiers in Public Health


The 12-hour Fundamentals of Health Research training offers a scalable model for strengthening research participation across populations. This five-part curriculum was co-developed and delivered by experienced CHW/Ps from the Community Engagement Core and included interactive components such as role-playing, IRB simulations, and the development of mock community-based research projects.

Between March and September 2023, 128 CHWs completed the training, with 103 (80.5%) completing the 12-month follow-up. Most participants identified as Latina (93%) and female (96%). Findings revealed a 46.8% increase in research knowledge, a 49.1% increase in likelihood of participating in research, and an average self-efficacy rating of 8 out of 10 for communicating about research. Over half (53.9%) reported referring individuals to research studies post-training. Qualitative findings further emphasized increased understanding of research ethics, persistent mistrust in research settings, and the potential for long-term impact.

By documenting the development, implementation, and evaluation of this training, the paper contributes to the field by identifying best practices for engaging CHW/Ps and assessing the program’s effectiveness through a mixed-methods approach. Read the paper here.