Daryl Davies, PhD, associate professor of clinical pharmacy, USC School of Pharmacy, and his collaborators at the University of Southern California (USC) and Children’s Hospital Los Angeles (CHLA) discovered that ivermectin, a drug used to treat parasitic infections in millions …
The SC CTSI helped researchers accelerate the development of a stem cell-based therapy that regenerates gut tissue lost to necrotizing enterocolitis, a complication that can affect prematurely born infants. Pediatric surgeon Tracy Grikscheit, MD, assistant professor of surgery, …
The SC CTSI funded research to identify ethnic variations in genetic mutations of factor VIII, a protein involved in blood clotting, which functions improperly in people with hemophilia A. Therapy for hemophilia involves infusing patients with replacement factor VIII protein, th…
A multidisciplinary team of researchers from the USC Dana and David Dornsife College of Letters, Arts and Sciences and the USC School of Pharmacy demonstrated a way to generate potential new Human Immunodeficiency Virus (HIV) drugs by inhibiting a crucial enzyme in the HIV repli…
The SC CTSI helped create a computerized speech translation system to be used in clinics and hospitals. SpeechLinks is designed to translate between English and Spanish in near real time. “This is the first study of its kind in the United States that deals with the Spanish-speak…
Many drugs cannot pass from the bloodstream into the brain and spinal cord. When patients have cancers that involve these sites, it may be difficult to get important chemotherapies in to fight the cancer. Ellis Meng, PhD, professor of biomedical engineering, USC Viterbi School o…
Clinicians at CHLA have noted that obese children with acute leukemia benefit less from chemotherapy than normal weight children. Steven Mittelman, MD, PhD, associate professor of pediatrics and physiology & biophysics, Keck School of Medicine of USC and colleagues at The Sa…
An interdisciplinary team of researchers developed a tiny pacemaker for unborn babies with a fatal heart problem called fetal heart block. Fetal heart block is a condition that causes an extremely slow heart rate, which may not be adequate to sustain the circulation. Babies with…
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